Prof. Dr. Kerstin Hoffmann-Jacobsen

Lehrveranstaltungen

Bachelorstudiengang

Mathematik I 

Mathematik II jeweils für B.Eng. und KIA

Praktikum Physikalische Chemie

Abwasserbehandlungstechniken Vorlesung (Modul Chemische Technik II)

Abwasserbehandlungstechniken Praktikum

Masterstudiengang

Methoden der biophysikalischen Chemie 

Oberflächenanalytik (Modul Surface Science)

 

Die Unterlagen zu den Lehrveranstaltungen finden Sie in den entsprechenden moodle classrooms.

Research: Biophysical Chemistry Group

The research of Prof. Hoffmann-Jacobsen explores the interdisciplinary field of biophysical chemistry and wastewater treatment. Our main research interest is the investigation and application of enzymes in technical environments.

Enzymes are nature´s catalysts that increase the rate of virtually all the chemical reactions within cells.  Nowadays, the enzymes are developed as biocatalysts in various important industrial processes as pharmaceutical synthesis and can be found in many products of daily life, e.g. laundry detergent. Enzymes are intrinsically green catalysts as they are biodegradable and work under ambient conditions. We aim to develop new enzymatic biocatalysts for new technological applications including a mechanistic understanding of the biophysical processes taking place within biocatalysis. The main analytical technique  fluorescence spectroscopy.

Currently, we are working on the following projects

-        ChemZymeCoat (FHProfUnt, BMBF): Chemo-enzymatic Synthesis of Functionalized Polymers for Innovative - Green Coatings

-       Analysis of textile biocatalysts, i.e. lipases immobilized on textile carriers, for the production of intermediates for the pharmaceutical industry   (ZIM, cooperation Deutsches Textilforschungszentrum Nord-West gGmbH)

-        Investigation of the structure and dynamics of lipases in organic media

-        Fluorescence correlation spectroscopy near surfaces

-        Removal of trace contaminants from sewage

-        Valorization of industrial sewage by enzyme catalysis

We have a fully equipped laboratory for biophysical chemistry including synthesis and spectroscopic analysis. This includes fluorescence spectroscopy, fluorescence lifetime analysis and fluorescence correlation spectroscopy.  The equipment for wastewater technology comprises a model sewage plant, lab ozonation reactor and the relevant analysis equipment, e.g. TOC, ion chromatography, atom absorption spectroscopy.

There are always Bachelor and Master thesis projects available. Please contact Prof. Hoffmann-Jacobsen.

Publications

Link to fulltext of our recent article: Ingenbosch, K. N., Rousek, A., Wunschik, D., & Hoffmann-Jacobsen, K. (2019). A fluorescence-based activity assay for immobilized lipases in non-native media. Analytical biochemistry, 569, 22-27.

 

Link to Researchgate

CV

since 2011 Professor for Physical Chemistry at Niederrhein University of Applied Sciences (Hochschule Niederrhein) 

2008-2010 Scientist at Continental Tires (Hanover), material development  

2006-2008 Postdoc with Prof. T. Kiefhaber at the Biocenter in Basel and Technical University of Munich 

2005-2006 Manager at the the German Council of Sciences and Humanities

2005 Graduation at Humboldt University of Berlin

2002-2003 Vistiting Scientist at UCLA, Los Angeles, USA

2001-2005 Graduation studies at the Fritz-Haber-Institute of the Max-Planck Society, Berlin, under the supervision of Prof. H.J. Freund 

2001 Diploma in Chemistry at the University of Karlsruhe (KIT) 

1999 Erasmus student at University of Manchester Institute for Science and Technology (UMIST), UK

1995 A-level in Cologne, Germany